mouse ccl2 elisa kit Search Results


mouse ccl2 je mcp 1 quantikine elisa kit  (R&D Systems)
95
R&D Systems mouse ccl2 je mcp 1 quantikine elisa kit
( A–B ) Expression of Gdf15 mRNA and GDF-15 protein in the brain of eIF2B homozygous (HOM) or wild-type mice treated with DNL343 or vehicle. ( C–D ) GDF-15 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( E–F ) Expression of brain Gfap mRNA and plasma GFAP protein in eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( G–H ) GFAP protein levels in the CSF and plasma of VWMD patients and healthy controls. ( I–J ) TIMP-1 protein levels in the brain and CSF of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( K–L ) TIMP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( M–N ) Expression of the <t>Ccl2</t> transcript, which encodes the MCP-1 protein, and levels of MCP-1 protein in the brain of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( O–P ) MCP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( Q–R ) NfL protein levels in the CSF and plasma of VWMD patients and healthy controls. ( S ) Heatmap visualization of relative changes in NfL, GDF-15, GFAP, and MCP-1 in the CSF of VWMD patients vs healthy controls, presented in log 2 scale. VWMD patient ID#s correspond across (CSF) and (plasma). Statistical significance was set at p<0.05. For all animal model panels, DNL343 dose is indicated on the x-axis and data is presented as mean ± SEM of N=9–18 mice per group. Statistical significance for DNL343 effect in the mouse model was determined by a one-way ANOVA followed by Dunn’s multiple comparison tests against vehicle-dosed animals of the same genotype (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001). Data from VWMD patients and healthy controls is presented as mean ± SEM. Statistical significance for the difference between samples from VWMD patients and healthy controls was assessed on log 2 fold change data using Welch’s t test (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001).
Mouse Ccl2 Je Mcp 1 Quantikine Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mouse ccl2 je mcp 1 quantikine elisa kit/product/R&D Systems
Average 95 stars, based on 1 article reviews
mouse ccl2 je mcp 1 quantikine elisa kit - by Bioz Stars, 2026-02
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mouse ccl2 mcp 1 elisa kit  (Multi Sciences (Lianke) Biotech Co Ltd)
94
Multi Sciences (Lianke) Biotech Co Ltd mouse ccl2 mcp 1 elisa kit
( A–B ) Expression of Gdf15 mRNA and GDF-15 protein in the brain of eIF2B homozygous (HOM) or wild-type mice treated with DNL343 or vehicle. ( C–D ) GDF-15 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( E–F ) Expression of brain Gfap mRNA and plasma GFAP protein in eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( G–H ) GFAP protein levels in the CSF and plasma of VWMD patients and healthy controls. ( I–J ) TIMP-1 protein levels in the brain and CSF of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( K–L ) TIMP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( M–N ) Expression of the <t>Ccl2</t> transcript, which encodes the MCP-1 protein, and levels of MCP-1 protein in the brain of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( O–P ) MCP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( Q–R ) NfL protein levels in the CSF and plasma of VWMD patients and healthy controls. ( S ) Heatmap visualization of relative changes in NfL, GDF-15, GFAP, and MCP-1 in the CSF of VWMD patients vs healthy controls, presented in log 2 scale. VWMD patient ID#s correspond across (CSF) and (plasma). Statistical significance was set at p<0.05. For all animal model panels, DNL343 dose is indicated on the x-axis and data is presented as mean ± SEM of N=9–18 mice per group. Statistical significance for DNL343 effect in the mouse model was determined by a one-way ANOVA followed by Dunn’s multiple comparison tests against vehicle-dosed animals of the same genotype (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001). Data from VWMD patients and healthy controls is presented as mean ± SEM. Statistical significance for the difference between samples from VWMD patients and healthy controls was assessed on log 2 fold change data using Welch’s t test (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001).
Mouse Ccl2 Mcp 1 Elisa Kit, supplied by Multi Sciences (Lianke) Biotech Co Ltd, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mouse ccl2 mcp 1 elisa kit/product/Multi Sciences (Lianke) Biotech Co Ltd
Average 94 stars, based on 1 article reviews
mouse ccl2 mcp 1 elisa kit - by Bioz Stars, 2026-02
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mouse ccl2 mcp 1 quantikine elisa kit  (R&D Systems)
96
R&D Systems mouse ccl2 mcp 1 quantikine elisa kit
( A–B ) Expression of Gdf15 mRNA and GDF-15 protein in the brain of eIF2B homozygous (HOM) or wild-type mice treated with DNL343 or vehicle. ( C–D ) GDF-15 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( E–F ) Expression of brain Gfap mRNA and plasma GFAP protein in eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( G–H ) GFAP protein levels in the CSF and plasma of VWMD patients and healthy controls. ( I–J ) TIMP-1 protein levels in the brain and CSF of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( K–L ) TIMP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( M–N ) Expression of the <t>Ccl2</t> transcript, which encodes the MCP-1 protein, and levels of MCP-1 protein in the brain of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( O–P ) MCP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( Q–R ) NfL protein levels in the CSF and plasma of VWMD patients and healthy controls. ( S ) Heatmap visualization of relative changes in NfL, GDF-15, GFAP, and MCP-1 in the CSF of VWMD patients vs healthy controls, presented in log 2 scale. VWMD patient ID#s correspond across (CSF) and (plasma). Statistical significance was set at p<0.05. For all animal model panels, DNL343 dose is indicated on the x-axis and data is presented as mean ± SEM of N=9–18 mice per group. Statistical significance for DNL343 effect in the mouse model was determined by a one-way ANOVA followed by Dunn’s multiple comparison tests against vehicle-dosed animals of the same genotype (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001). Data from VWMD patients and healthy controls is presented as mean ± SEM. Statistical significance for the difference between samples from VWMD patients and healthy controls was assessed on log 2 fold change data using Welch’s t test (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001).
Mouse Ccl2 Mcp 1 Quantikine Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
mouse ccl2 mcp 1 quantikine elisa kit - by Bioz Stars, 2026-02
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mouse mcp 1 elisa kit  (Proteintech)
93
Proteintech mouse mcp 1 elisa kit
( A–B ) Expression of Gdf15 mRNA and GDF-15 protein in the brain of eIF2B homozygous (HOM) or wild-type mice treated with DNL343 or vehicle. ( C–D ) GDF-15 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( E–F ) Expression of brain Gfap mRNA and plasma GFAP protein in eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( G–H ) GFAP protein levels in the CSF and plasma of VWMD patients and healthy controls. ( I–J ) TIMP-1 protein levels in the brain and CSF of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( K–L ) TIMP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( M–N ) Expression of the <t>Ccl2</t> transcript, which encodes the MCP-1 protein, and levels of MCP-1 protein in the brain of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( O–P ) MCP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( Q–R ) NfL protein levels in the CSF and plasma of VWMD patients and healthy controls. ( S ) Heatmap visualization of relative changes in NfL, GDF-15, GFAP, and MCP-1 in the CSF of VWMD patients vs healthy controls, presented in log 2 scale. VWMD patient ID#s correspond across (CSF) and (plasma). Statistical significance was set at p<0.05. For all animal model panels, DNL343 dose is indicated on the x-axis and data is presented as mean ± SEM of N=9–18 mice per group. Statistical significance for DNL343 effect in the mouse model was determined by a one-way ANOVA followed by Dunn’s multiple comparison tests against vehicle-dosed animals of the same genotype (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001). Data from VWMD patients and healthy controls is presented as mean ± SEM. Statistical significance for the difference between samples from VWMD patients and healthy controls was assessed on log 2 fold change data using Welch’s t test (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001).
Mouse Mcp 1 Elisa Kit, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse mcp 1 elisa kit - by Bioz Stars, 2026-02
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mouse mcp 1 elisa assay kit  (R&D Systems)
93
R&D Systems mouse mcp 1 elisa assay kit
( A–B ) Expression of Gdf15 mRNA and GDF-15 protein in the brain of eIF2B homozygous (HOM) or wild-type mice treated with DNL343 or vehicle. ( C–D ) GDF-15 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( E–F ) Expression of brain Gfap mRNA and plasma GFAP protein in eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( G–H ) GFAP protein levels in the CSF and plasma of VWMD patients and healthy controls. ( I–J ) TIMP-1 protein levels in the brain and CSF of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( K–L ) TIMP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( M–N ) Expression of the <t>Ccl2</t> transcript, which encodes the MCP-1 protein, and levels of MCP-1 protein in the brain of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( O–P ) MCP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( Q–R ) NfL protein levels in the CSF and plasma of VWMD patients and healthy controls. ( S ) Heatmap visualization of relative changes in NfL, GDF-15, GFAP, and MCP-1 in the CSF of VWMD patients vs healthy controls, presented in log 2 scale. VWMD patient ID#s correspond across (CSF) and (plasma). Statistical significance was set at p<0.05. For all animal model panels, DNL343 dose is indicated on the x-axis and data is presented as mean ± SEM of N=9–18 mice per group. Statistical significance for DNL343 effect in the mouse model was determined by a one-way ANOVA followed by Dunn’s multiple comparison tests against vehicle-dosed animals of the same genotype (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001). Data from VWMD patients and healthy controls is presented as mean ± SEM. Statistical significance for the difference between samples from VWMD patients and healthy controls was assessed on log 2 fold change data using Welch’s t test (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001).
Mouse Mcp 1 Elisa Assay Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse mcp 1 elisa assay kit - by Bioz Stars, 2026-02
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2 monocyte chemotactic protein 1  (Boster Bio)
93
Boster Bio 2 monocyte chemotactic protein 1
( A–B ) Expression of Gdf15 mRNA and GDF-15 protein in the brain of eIF2B homozygous (HOM) or wild-type mice treated with DNL343 or vehicle. ( C–D ) GDF-15 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( E–F ) Expression of brain Gfap mRNA and plasma GFAP protein in eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( G–H ) GFAP protein levels in the CSF and plasma of VWMD patients and healthy controls. ( I–J ) TIMP-1 protein levels in the brain and CSF of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( K–L ) TIMP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( M–N ) Expression of the <t>Ccl2</t> transcript, which encodes the MCP-1 protein, and levels of MCP-1 protein in the brain of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( O–P ) MCP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( Q–R ) NfL protein levels in the CSF and plasma of VWMD patients and healthy controls. ( S ) Heatmap visualization of relative changes in NfL, GDF-15, GFAP, and MCP-1 in the CSF of VWMD patients vs healthy controls, presented in log 2 scale. VWMD patient ID#s correspond across (CSF) and (plasma). Statistical significance was set at p<0.05. For all animal model panels, DNL343 dose is indicated on the x-axis and data is presented as mean ± SEM of N=9–18 mice per group. Statistical significance for DNL343 effect in the mouse model was determined by a one-way ANOVA followed by Dunn’s multiple comparison tests against vehicle-dosed animals of the same genotype (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001). Data from VWMD patients and healthy controls is presented as mean ± SEM. Statistical significance for the difference between samples from VWMD patients and healthy controls was assessed on log 2 fold change data using Welch’s t test (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001).
2 Monocyte Chemotactic Protein 1, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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monocyte chemoattractant protein-1 (mcp-1) finetest eh022  (FineTest Biotech Inc)
90
FineTest Biotech Inc monocyte chemoattractant protein-1 (mcp-1) finetest eh022
( A–B ) Expression of Gdf15 mRNA and GDF-15 protein in the brain of eIF2B homozygous (HOM) or wild-type mice treated with DNL343 or vehicle. ( C–D ) GDF-15 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( E–F ) Expression of brain Gfap mRNA and plasma GFAP protein in eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( G–H ) GFAP protein levels in the CSF and plasma of VWMD patients and healthy controls. ( I–J ) TIMP-1 protein levels in the brain and CSF of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( K–L ) TIMP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( M–N ) Expression of the <t>Ccl2</t> transcript, which encodes the MCP-1 protein, and levels of MCP-1 protein in the brain of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( O–P ) MCP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( Q–R ) NfL protein levels in the CSF and plasma of VWMD patients and healthy controls. ( S ) Heatmap visualization of relative changes in NfL, GDF-15, GFAP, and MCP-1 in the CSF of VWMD patients vs healthy controls, presented in log 2 scale. VWMD patient ID#s correspond across (CSF) and (plasma). Statistical significance was set at p<0.05. For all animal model panels, DNL343 dose is indicated on the x-axis and data is presented as mean ± SEM of N=9–18 mice per group. Statistical significance for DNL343 effect in the mouse model was determined by a one-way ANOVA followed by Dunn’s multiple comparison tests against vehicle-dosed animals of the same genotype (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001). Data from VWMD patients and healthy controls is presented as mean ± SEM. Statistical significance for the difference between samples from VWMD patients and healthy controls was assessed on log 2 fold change data using Welch’s t test (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001).
Monocyte Chemoattractant Protein 1 (Mcp 1) Finetest Eh022, supplied by FineTest Biotech Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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monocyte chemokine protein-1 (mcp-1  (Cloud-Clone corp)
90
Cloud-Clone corp monocyte chemokine protein-1 (mcp-1
Hepatic oxidative stress and inflammation in normal or diabetic rats. (a) Nuclear 8-OHdG (400x) detected by IHC staining and IOD assessed by Image-J. (b) Serum H 2 O 2 levels. (c) Hepatic MDA levels. (d) Hepatic 8-isoprostane determined by ELISA. (e) Hepatic inflammatory cytokines determined by ELISA. Data are expressed as mean ± SEM ( n = 9 per group). △ P < 0.05 versus normal sham group; △△ P < 0.01 versus normal sham group; △△△ P < 0.001 versus normal sham group; ◊ P < 0.05 versus diabetic sham group; ◊◊ P < 0.01 versus diabetic sham group; ◊◊◊ P < 0.001 versus diabetic sham group; # P < 0.05 versus normal HIRI group; ## P < 0.01 versus normal HIRI group; ### P < 0.001 versus normal HIRI group. HIRI: hepatic ischemia reperfusion injury; 8-OHdG: 8-hydroxydeoxyguanosine; IOD: integrated optical intensity; IHC: immunohistochemistry; H 2 O 2 : hydrogen peroxide; MDA: malondialdehyde; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine <t>protein-1;</t> IL-6: interleukin-6; ELISA: enzyme-linked immunosorbent assay; sham: sham operating group.
Monocyte Chemokine Protein 1 (Mcp 1, supplied by Cloud-Clone corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse monocyte chemotactic protein 1 (mcp-1/ ccl2/mcaf) elisa kit  (CUSAg Inc)
90
CUSAg Inc mouse monocyte chemotactic protein 1 (mcp-1/ ccl2/mcaf) elisa kit
Hepatic oxidative stress and inflammation in normal or diabetic rats. (a) Nuclear 8-OHdG (400x) detected by IHC staining and IOD assessed by Image-J. (b) Serum H 2 O 2 levels. (c) Hepatic MDA levels. (d) Hepatic 8-isoprostane determined by ELISA. (e) Hepatic inflammatory cytokines determined by ELISA. Data are expressed as mean ± SEM ( n = 9 per group). △ P < 0.05 versus normal sham group; △△ P < 0.01 versus normal sham group; △△△ P < 0.001 versus normal sham group; ◊ P < 0.05 versus diabetic sham group; ◊◊ P < 0.01 versus diabetic sham group; ◊◊◊ P < 0.001 versus diabetic sham group; # P < 0.05 versus normal HIRI group; ## P < 0.01 versus normal HIRI group; ### P < 0.001 versus normal HIRI group. HIRI: hepatic ischemia reperfusion injury; 8-OHdG: 8-hydroxydeoxyguanosine; IOD: integrated optical intensity; IHC: immunohistochemistry; H 2 O 2 : hydrogen peroxide; MDA: malondialdehyde; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine <t>protein-1;</t> IL-6: interleukin-6; ELISA: enzyme-linked immunosorbent assay; sham: sham operating group.
Mouse Monocyte Chemotactic Protein 1 (Mcp 1/ Ccl2/Mcaf) Elisa Kit, supplied by CUSAg Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse ccl2/mcp-1 high sensitivity elisa kit  (Multi Sciences (Lianke) Biotech Co Ltd)
99
Multi Sciences (Lianke) Biotech Co Ltd mouse ccl2/mcp-1 high sensitivity elisa kit
Hepatic oxidative stress and inflammation in normal or diabetic rats. (a) Nuclear 8-OHdG (400x) detected by IHC staining and IOD assessed by Image-J. (b) Serum H 2 O 2 levels. (c) Hepatic MDA levels. (d) Hepatic 8-isoprostane determined by ELISA. (e) Hepatic inflammatory cytokines determined by ELISA. Data are expressed as mean ± SEM ( n = 9 per group). △ P < 0.05 versus normal sham group; △△ P < 0.01 versus normal sham group; △△△ P < 0.001 versus normal sham group; ◊ P < 0.05 versus diabetic sham group; ◊◊ P < 0.01 versus diabetic sham group; ◊◊◊ P < 0.001 versus diabetic sham group; # P < 0.05 versus normal HIRI group; ## P < 0.01 versus normal HIRI group; ### P < 0.001 versus normal HIRI group. HIRI: hepatic ischemia reperfusion injury; 8-OHdG: 8-hydroxydeoxyguanosine; IOD: integrated optical intensity; IHC: immunohistochemistry; H 2 O 2 : hydrogen peroxide; MDA: malondialdehyde; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine <t>protein-1;</t> IL-6: interleukin-6; ELISA: enzyme-linked immunosorbent assay; sham: sham operating group.
Mouse Ccl2/Mcp 1 High Sensitivity Elisa Kit, supplied by Multi Sciences (Lianke) Biotech Co Ltd, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse ccl2/je/mcp-1 duoset elisa  (Bio-Techne corporation)
96
Bio-Techne corporation mouse ccl2/je/mcp-1 duoset elisa
Hepatic oxidative stress and inflammation in normal or diabetic rats. (a) Nuclear 8-OHdG (400x) detected by IHC staining and IOD assessed by Image-J. (b) Serum H 2 O 2 levels. (c) Hepatic MDA levels. (d) Hepatic 8-isoprostane determined by ELISA. (e) Hepatic inflammatory cytokines determined by ELISA. Data are expressed as mean ± SEM ( n = 9 per group). △ P < 0.05 versus normal sham group; △△ P < 0.01 versus normal sham group; △△△ P < 0.001 versus normal sham group; ◊ P < 0.05 versus diabetic sham group; ◊◊ P < 0.01 versus diabetic sham group; ◊◊◊ P < 0.001 versus diabetic sham group; # P < 0.05 versus normal HIRI group; ## P < 0.01 versus normal HIRI group; ### P < 0.001 versus normal HIRI group. HIRI: hepatic ischemia reperfusion injury; 8-OHdG: 8-hydroxydeoxyguanosine; IOD: integrated optical intensity; IHC: immunohistochemistry; H 2 O 2 : hydrogen peroxide; MDA: malondialdehyde; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine <t>protein-1;</t> IL-6: interleukin-6; ELISA: enzyme-linked immunosorbent assay; sham: sham operating group.
Mouse Ccl2/Je/Mcp 1 Duoset Elisa, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse ccl2/je/mcp-1 duoset elisa - by Bioz Stars, 2026-02
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mouse picokinetm elisa kit  (Boster Bio)
91
Boster Bio mouse picokinetm elisa kit
Hepatic oxidative stress and inflammation in normal or diabetic rats. (a) Nuclear 8-OHdG (400x) detected by IHC staining and IOD assessed by Image-J. (b) Serum H 2 O 2 levels. (c) Hepatic MDA levels. (d) Hepatic 8-isoprostane determined by ELISA. (e) Hepatic inflammatory cytokines determined by ELISA. Data are expressed as mean ± SEM ( n = 9 per group). △ P < 0.05 versus normal sham group; △△ P < 0.01 versus normal sham group; △△△ P < 0.001 versus normal sham group; ◊ P < 0.05 versus diabetic sham group; ◊◊ P < 0.01 versus diabetic sham group; ◊◊◊ P < 0.001 versus diabetic sham group; # P < 0.05 versus normal HIRI group; ## P < 0.01 versus normal HIRI group; ### P < 0.001 versus normal HIRI group. HIRI: hepatic ischemia reperfusion injury; 8-OHdG: 8-hydroxydeoxyguanosine; IOD: integrated optical intensity; IHC: immunohistochemistry; H 2 O 2 : hydrogen peroxide; MDA: malondialdehyde; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine <t>protein-1;</t> IL-6: interleukin-6; ELISA: enzyme-linked immunosorbent assay; sham: sham operating group.
Mouse Picokinetm Elisa Kit, supplied by Boster Bio, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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( A–B ) Expression of Gdf15 mRNA and GDF-15 protein in the brain of eIF2B homozygous (HOM) or wild-type mice treated with DNL343 or vehicle. ( C–D ) GDF-15 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( E–F ) Expression of brain Gfap mRNA and plasma GFAP protein in eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( G–H ) GFAP protein levels in the CSF and plasma of VWMD patients and healthy controls. ( I–J ) TIMP-1 protein levels in the brain and CSF of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( K–L ) TIMP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( M–N ) Expression of the Ccl2 transcript, which encodes the MCP-1 protein, and levels of MCP-1 protein in the brain of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( O–P ) MCP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( Q–R ) NfL protein levels in the CSF and plasma of VWMD patients and healthy controls. ( S ) Heatmap visualization of relative changes in NfL, GDF-15, GFAP, and MCP-1 in the CSF of VWMD patients vs healthy controls, presented in log 2 scale. VWMD patient ID#s correspond across (CSF) and (plasma). Statistical significance was set at p<0.05. For all animal model panels, DNL343 dose is indicated on the x-axis and data is presented as mean ± SEM of N=9–18 mice per group. Statistical significance for DNL343 effect in the mouse model was determined by a one-way ANOVA followed by Dunn’s multiple comparison tests against vehicle-dosed animals of the same genotype (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001). Data from VWMD patients and healthy controls is presented as mean ± SEM. Statistical significance for the difference between samples from VWMD patients and healthy controls was assessed on log 2 fold change data using Welch’s t test (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001).

Journal: eLife

Article Title: DNL343 is an investigational CNS penetrant eukaryotic initiation factor 2B activator that prevents and reverses the effects of neurodegeneration caused by the integrated stress response

doi: 10.7554/eLife.92173

Figure Lengend Snippet: ( A–B ) Expression of Gdf15 mRNA and GDF-15 protein in the brain of eIF2B homozygous (HOM) or wild-type mice treated with DNL343 or vehicle. ( C–D ) GDF-15 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( E–F ) Expression of brain Gfap mRNA and plasma GFAP protein in eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( G–H ) GFAP protein levels in the CSF and plasma of VWMD patients and healthy controls. ( I–J ) TIMP-1 protein levels in the brain and CSF of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( K–L ) TIMP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( M–N ) Expression of the Ccl2 transcript, which encodes the MCP-1 protein, and levels of MCP-1 protein in the brain of eIF2B HOM or wild-type mice treated with DNL343 or vehicle. ( O–P ) MCP-1 protein levels in the CSF and plasma of VWMD patients and healthy controls. ( Q–R ) NfL protein levels in the CSF and plasma of VWMD patients and healthy controls. ( S ) Heatmap visualization of relative changes in NfL, GDF-15, GFAP, and MCP-1 in the CSF of VWMD patients vs healthy controls, presented in log 2 scale. VWMD patient ID#s correspond across (CSF) and (plasma). Statistical significance was set at p<0.05. For all animal model panels, DNL343 dose is indicated on the x-axis and data is presented as mean ± SEM of N=9–18 mice per group. Statistical significance for DNL343 effect in the mouse model was determined by a one-way ANOVA followed by Dunn’s multiple comparison tests against vehicle-dosed animals of the same genotype (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001). Data from VWMD patients and healthy controls is presented as mean ± SEM. Statistical significance for the difference between samples from VWMD patients and healthy controls was assessed on log 2 fold change data using Welch’s t test (*, p<0.05. **, p<0.01, ***, p<0.001, ****, p<0.0001).

Article Snippet: ELISA kits were used to determine the levels of GDF-15 (mouse/rat GDF-15 Quantikine ELISA Kit, R&D Systems, catalog # MGD150), TIMP-1 (mouse TIMP-1 Quantikine ELISA Kit, R&D Systems, catalog # MTM100), and MCP-1 (Mouse CCL2/JE/MCP-1 Quantikine ELISA Kit, R&D Systems, catalog # MJE00B) in the brain, plasma, or CSF samples.

Techniques: Expressing, Animal Model, Comparison

Hepatic oxidative stress and inflammation in normal or diabetic rats. (a) Nuclear 8-OHdG (400x) detected by IHC staining and IOD assessed by Image-J. (b) Serum H 2 O 2 levels. (c) Hepatic MDA levels. (d) Hepatic 8-isoprostane determined by ELISA. (e) Hepatic inflammatory cytokines determined by ELISA. Data are expressed as mean ± SEM ( n = 9 per group). △ P < 0.05 versus normal sham group; △△ P < 0.01 versus normal sham group; △△△ P < 0.001 versus normal sham group; ◊ P < 0.05 versus diabetic sham group; ◊◊ P < 0.01 versus diabetic sham group; ◊◊◊ P < 0.001 versus diabetic sham group; # P < 0.05 versus normal HIRI group; ## P < 0.01 versus normal HIRI group; ### P < 0.001 versus normal HIRI group. HIRI: hepatic ischemia reperfusion injury; 8-OHdG: 8-hydroxydeoxyguanosine; IOD: integrated optical intensity; IHC: immunohistochemistry; H 2 O 2 : hydrogen peroxide; MDA: malondialdehyde; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine protein-1; IL-6: interleukin-6; ELISA: enzyme-linked immunosorbent assay; sham: sham operating group.

Journal: Oxidative Medicine and Cellular Longevity

Article Title: Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation

doi: 10.1155/2016/3919627

Figure Lengend Snippet: Hepatic oxidative stress and inflammation in normal or diabetic rats. (a) Nuclear 8-OHdG (400x) detected by IHC staining and IOD assessed by Image-J. (b) Serum H 2 O 2 levels. (c) Hepatic MDA levels. (d) Hepatic 8-isoprostane determined by ELISA. (e) Hepatic inflammatory cytokines determined by ELISA. Data are expressed as mean ± SEM ( n = 9 per group). △ P < 0.05 versus normal sham group; △△ P < 0.01 versus normal sham group; △△△ P < 0.001 versus normal sham group; ◊ P < 0.05 versus diabetic sham group; ◊◊ P < 0.01 versus diabetic sham group; ◊◊◊ P < 0.001 versus diabetic sham group; # P < 0.05 versus normal HIRI group; ## P < 0.01 versus normal HIRI group; ### P < 0.001 versus normal HIRI group. HIRI: hepatic ischemia reperfusion injury; 8-OHdG: 8-hydroxydeoxyguanosine; IOD: integrated optical intensity; IHC: immunohistochemistry; H 2 O 2 : hydrogen peroxide; MDA: malondialdehyde; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine protein-1; IL-6: interleukin-6; ELISA: enzyme-linked immunosorbent assay; sham: sham operating group.

Article Snippet: Rat-specific ELISA kits were applied to determine hepatic and medium tumor necrosis factor α (TNF- α , SEA133Ra, USCN, Cloud-Clone Corp., Wuhan, China), monocyte chemokine protein-1 (MCP-1, SEA087Mi, USCN, Cloud-Clone Corp., Wuhan, China), and hepatic interleukin-6 (IL-6, SEA079Ra, USCN, Cloud-Clone Corp., Wuhan, China) and levels according to the manufacturer's instructions.

Techniques: Immunohistochemistry, Enzyme-linked Immunosorbent Assay

High glucose culture increases ROS generation and cytokines release within BRL-3A hepatocytes. ((a), (b)) Intracellular ROS stained by 6-carboxy-2′7′-DCFH-DA (200x) and the fluorescence intensity was detected by fluorescence spectrophotometer. ((c), (d)) TNF- α and MCP-1 in the culture medium. ▲ P < 0.05 versus 5.5 mM control group; ⧫ P < 0.05 versus 25 mM control group; # P < 0.05 versus 5.5 mM H/R group. H/R: hypoxia/reoxygenation; ROS: reactive oxygen species; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine protein-1.

Journal: Oxidative Medicine and Cellular Longevity

Article Title: Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation

doi: 10.1155/2016/3919627

Figure Lengend Snippet: High glucose culture increases ROS generation and cytokines release within BRL-3A hepatocytes. ((a), (b)) Intracellular ROS stained by 6-carboxy-2′7′-DCFH-DA (200x) and the fluorescence intensity was detected by fluorescence spectrophotometer. ((c), (d)) TNF- α and MCP-1 in the culture medium. ▲ P < 0.05 versus 5.5 mM control group; ⧫ P < 0.05 versus 25 mM control group; # P < 0.05 versus 5.5 mM H/R group. H/R: hypoxia/reoxygenation; ROS: reactive oxygen species; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine protein-1.

Article Snippet: Rat-specific ELISA kits were applied to determine hepatic and medium tumor necrosis factor α (TNF- α , SEA133Ra, USCN, Cloud-Clone Corp., Wuhan, China), monocyte chemokine protein-1 (MCP-1, SEA087Mi, USCN, Cloud-Clone Corp., Wuhan, China), and hepatic interleukin-6 (IL-6, SEA079Ra, USCN, Cloud-Clone Corp., Wuhan, China) and levels according to the manufacturer's instructions.

Techniques: Staining, Fluorescence, Spectrophotometry

Hepatic ischemia reperfusion injury, oxidative stress, and inflammation in NAC or apocynin pretreated diabetic rats. ((a), (b)) Hepatic pathology sections (200x), pathological scores, and serum transferase. (c) Hepatic inflammatory cytokines levels. ((d), (e)) Nuclear 8-OHdG (400x) detected by IHC staining and IOD assessed by Image-J; (f) MDA levels; (g) 8-isoprostane levels by ELISA. Measurable data are expressed as mean ± SEM ( n = 5 per group). Pathology scores are expressed as medium with interquartile range. ◊ P < 0.05 versus sham group; ◊◊ P < 0.01 versus sham group; ◊◊◊ P < 0.001 versus sham group; # P < 0.05 versus HIRI group; ## P < 0.01 versus HIRI group; ### P < 0.001 versus HIRI group. HIRI: hepatic ischemia reperfusion injury; NAC: N-acetyl-L-cysteine; IHC: immunohistochemistry; 8-OHdG: 8-hydroxydeoxyguanosine; IOD: integrated optical intensity; MDA: malondialdehyde; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine protein-1; IL-6: interleukin-6; ELISA: enzyme-linked immunosorbent assay; sham: sham operating group.

Journal: Oxidative Medicine and Cellular Longevity

Article Title: Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation

doi: 10.1155/2016/3919627

Figure Lengend Snippet: Hepatic ischemia reperfusion injury, oxidative stress, and inflammation in NAC or apocynin pretreated diabetic rats. ((a), (b)) Hepatic pathology sections (200x), pathological scores, and serum transferase. (c) Hepatic inflammatory cytokines levels. ((d), (e)) Nuclear 8-OHdG (400x) detected by IHC staining and IOD assessed by Image-J; (f) MDA levels; (g) 8-isoprostane levels by ELISA. Measurable data are expressed as mean ± SEM ( n = 5 per group). Pathology scores are expressed as medium with interquartile range. ◊ P < 0.05 versus sham group; ◊◊ P < 0.01 versus sham group; ◊◊◊ P < 0.001 versus sham group; # P < 0.05 versus HIRI group; ## P < 0.01 versus HIRI group; ### P < 0.001 versus HIRI group. HIRI: hepatic ischemia reperfusion injury; NAC: N-acetyl-L-cysteine; IHC: immunohistochemistry; 8-OHdG: 8-hydroxydeoxyguanosine; IOD: integrated optical intensity; MDA: malondialdehyde; TNF- α : tumor necrosis factor α ; MCP-1: monocyte chemokine protein-1; IL-6: interleukin-6; ELISA: enzyme-linked immunosorbent assay; sham: sham operating group.

Article Snippet: Rat-specific ELISA kits were applied to determine hepatic and medium tumor necrosis factor α (TNF- α , SEA133Ra, USCN, Cloud-Clone Corp., Wuhan, China), monocyte chemokine protein-1 (MCP-1, SEA087Mi, USCN, Cloud-Clone Corp., Wuhan, China), and hepatic interleukin-6 (IL-6, SEA079Ra, USCN, Cloud-Clone Corp., Wuhan, China) and levels according to the manufacturer's instructions.

Techniques: Immunohistochemistry, Enzyme-linked Immunosorbent Assay